Del Potro hasn't played a singles rubber in the Davis Cup for four years following three wrist operations that nearly saw him quit the game.
"It's going to be really tough, a tough moment for me against Andy". It was my longest match of my career and I won it against Andy playing here.
The Olympic gold medal was on the line the last time Andy Murray met Juan Martin del Potro on court in Rio.
The must-win rubber for the holders in the worldwide team competition took almost three hours, putting Andy Murray's court time over two weekend matches at eight hours.
The second semi-final between France and Croatia is evenly poised after the opening singles matches as Richard Gasquet and Marin Cilic started with wins. "We'll see if I can give the first point to my team".
Kyle Edmund is under big pressure to get Great Britain off the mark as he takes on Guido Pella in Friday night's other singles match.
Del Potro's resurgence has been the feel-good story of the summer and it would be a hard-hearted person who was not at least a little bit happy for the genial 27-year-old.
We have no doubt that Andy will be playing with his grandfather in mind, and wish him all of the best in his bid to become Davis Cup champion for the second year running. "We are very proud as a team what we have achieved so far so all you can ask is that we go out and fight".
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The pair were given a huge ovation as they prepared to do an on-court interview, and Jamie's voice cracked as he said: " It's not going to get better for me than to play with him in front of a Scottish crowd". But I've never played a match that long.
Dan Evans missed the last tie with a shoulder injury, but is back to replace James Ward after coming within one point of beating Stan Wawrinka in the third round of the US Open before losing in five sets.
Britain is attempting to retain the Davis Cup for the first time since 1936, having won the tournament for the first time in 79 years in November.
Andy Murray, of the United Kingdom, reacts after losing a game in the fifth set of his match with Kei Nishikori, of Japan, during the quarterfinals of the U.S. Open tennis tournament, Wednesday, Sept. 7, 2016, in NY.
Murray - the current world number two - did not allow that setback to disrupt his gameplan and took both of the next two sets by producing some brilliant, pinpoint tennis in a match that was fast becoming a Davis Cup classic. "I think we made a good choice with the captain to play Andy on the first day". "I want to play for more years, not just one more match".
Smith is hoping home advantage will also come into play.
Sunday will then see the reverse singles and Edmund who, in Andy Murray's absence, led Great Britain to victory over Serbia in the second round, will hope his enhanced Davis Cup experience and confidence will be beneficial in Glasgow. Fired up by this sense of injustice, the world number two produced some sublime tennis to win the next three games before taking the set on a tie break.
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