Indianapolis Colts vs Denver Broncos Sun. Sept. 26th 4:15pm EST
The Indianapolis Colts came into this NFL regular season with Super Bowl aspirations and practically every NFL analysts and former player backing them to go all the way this season and lift the Lombardi trophy for the second time in the Peyton Manning era, but after Week 1’s devastating loss to the division rival Houston Texans, many people started to question whether or not this defense could compliment the potent offense.
Fortunately, in Week 2 the defense did just that as Dwight Freeney and company had Peyton’s baby brother Eli running for his life with constant pressure on every snap made by the New York Giants. As a result, both the Colts offense and defense dominated on Sunday night and gave Indianapolis their first win of the season 38-14. The spread with this matchup has the Colts at -5.5 by Bodog, one of the top US A online sportsbooks anywhere.
In Week 3, Peyton Manning and his boys will look to keep a good thing going as they will travel to the Mile High City to take on Josh McDaniels’ Denver Broncos.
Even though the Indianapolis Colts are favored by -6 points to win this matchup against the Denver Broncos, I won’t be surprised to see the up and coming offense led by quarterback Kyle Orton give the Colts defense a run for their money.
Ultimately, I believe the Indianapolis Colts will come out on top and win their second straight game of the season, but the Broncos might be a tougher opponent than people will be anticipating as they proved last week against the Seattle Seahawks that they can put points on the board and hold offenses in check.
There will be two things to watch in this game as Peyton Manning could have a big day if Champ Bailey is watching from the sidelines and rookie Broncos wide receiver Demaryius Thomas will try to keep up his production against a weak Colts secondary. We recommend Bodog, DSI or Betus for this weeks NFL football betting action.
Related News
- NFL Week 5: Kansas City Chiefs vs Indianapolis Colts Sportsbook odds and predictions
- NFL Week 6: Indianapolis Colts vs Washington Redskins Sportsbook picks and odds
- NFL Week 6: New York Jets vs Denver Broncos Sportsbook Odds and Predictions
- NFL Week 5: Denver Broncos vs Baltimore Ravens Sportsbook odds and predictions
- Colts want Peyton Manning to become highest paid player in the NFL
One Response to “NFL Week 3: Indianapolis Colts vs Denver Broncos odds and predictions”
Leave a Reply
- NFL Week 8: Carolina Panthers vs St. Louis Rams Sportsbook odds and predictions
- NFL Week 8: Buffalo Bills vs Kansas City Chiefs Sportsbook odds and predictions
- Texas Rangers and San Francisco Giants Advance to the 2010 World Series
- NFL Week 7: San Francisco 49ers vs Carolina Panthers Sportsbook odds and predictions
- 2010 NLCS Game 6 – San Francisco Giants @ Philadelphia Phillies October 23, 2025 7:57 p.m. ET
- NFL Week 7: Minnesota Vikings vs Green Bay Packers odds and predictions
- NFL Week 7: Philadelphia Eagles vs Tennessee Titans Sportsbook odds and predictions
- NFL Week 7: New York Giants vs Dallas Cowboys odds and predictions
- 2010 ALCS Game 6 – New York Yankees @ Texas Rangers October 22, 2025 8:04 p.m. ET
- NFL Week 7: Jacksonville Jaguars vs Kansas City Chiefs Sportsbook odds and predictions
- James: I have Nicks starting tonight and need a nice showing or I am going down this week. Go Giants.
- Mike: I hope you’re right. I’ve got Eli/Nicks/Jacobs all starting tomorrow for fantasy. Jacobs has settle...
- Giant FAn: yea right, the giants are gonna whoop some cow-gurl butt on monday. The giants are playing not SUPRISINGLY...
- John Bryant: lets go Giants!
- Cassandra Lee: this was a fantastic article! my daughter rue and i are always watching the giants game and i have...
- Stacy: My mistake - I must have been thinking about the defenseman that hit him when I typed that. Thanks for...
- gurthmaeg: Great article until, the end. Franzen is not a defenseman. He is a forward, one of the top forwards on the...
- Natosha Thell: The Eagle offensive line is like a sieve. Kolb is lucky he doesn’t get a concussion on every...



What everybody think the unbeatens will be after this week? I am pretty sure it will be the Chiefs.